Yoshio Kase Selected Research

shakuyaku-kanzoh-toh

11/2015	Pharmacokinetic Profiles of Active Components After Oral Administration of a Kampo Medicine, Shakuyakukanzoto, to Healthy Adult Japanese Volunteers.
1/2013	Antispasmodic effect of shakuyakukanzoto extract on experimental muscle cramps in vivo: role of the active constituents of Glycyrrhizae radix.

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Yoshio Kase Research Topics

Disease

9	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2017 - 09/2009
6	Hot Flashes 01/2011 - 11/2003
5	Inflammation (Inflammations) 01/2017 - 02/2008
5	Pain (Aches) 01/2017 - 12/2006
5	Neoplasms (Cancer) 01/2017 - 02/2014
5	Dementia (Dementias) 05/2015 - 10/2009
4	Peripheral Nervous System Diseases (PNS Diseases) 11/2016 - 01/2012
4	Hyperalgesia 11/2016 - 12/2006
4	Nephritis 02/2011 - 03/2006
3	Body Weight (Weight, Body) 01/2017 - 03/2007
3	Cachexia 01/2017 - 02/2014
3	Stomatitis 06/2016 - 01/2015
3	Hypersensitivity (Allergy) 06/2016 - 12/2002
2	Anorexia 01/2017 - 02/2014
2	Oral Ulcer (Mouth Ulcer) 01/2017 - 06/2016
2	Cold Hypersensitivity 11/2016 - 01/2014
2	Muscle Cramp (Cramp) 11/2015 - 01/2013
2	Acne Vulgaris 09/2015 - 01/2015
2	Skin Diseases (Skin Disease) 09/2015 - 01/2015
2	Atherosclerosis 01/2013 - 05/2008
2	Insulin Resistance 06/2012 - 05/2008
2	Leiomyoma (Uterine Fibroids) 06/2012 - 08/2011
2	Atopic Dermatitis (Atopic Eczema) 11/2011 - 10/2009
2	Learning Disabilities (Learning Disability) 04/2011 - 10/2010
2	Thiamine Deficiency 10/2010 - 01/2010
2	Alzheimer Disease (Alzheimer's Disease) 06/2009 - 02/2009
2	Ischemia 09/2006 - 03/2002
2	Prostatic Neoplasms (Prostate Cancer) 11/2004 - 11/2003
1	Intestinal Pseudo-Obstruction (Intestinal Pseudoobstruction) 01/2018
1	Mucositis 01/2017
1	Human Influenza (Influenza) 01/2017
1	Stomach Neoplasms (Stomach Cancer) 01/2017
1	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2017
1	Respiratory Tract Infections (Respiratory Tract Infection) 01/2017
1	Ulcer 06/2016
1	Dyskinesias (Dyskinesia) 01/2016
1	Knee Osteoarthritis 12/2015
1	Arthralgia (Joint Pain) 12/2015
1	Hydrarthrosis 12/2015
1	Hyperesthesia 11/2015
1	Atrophy 11/2015
1	Paresthesia (Dysesthesia) 11/2015
1	Hypesthesia (Numbness) 11/2015
1	Abdominal Pain (Pain, Abdominal) 11/2015

Drug/Important Bio-Agent (IBA)

17	Yi-Gan SanIBA 01/2016 - 02/2009
6	CytokinesIBA 01/2013 - 08/2006
5	Calcitonin Gene-Related PeptideIBA 06/2007 - 03/2002
4	liu-jun-zi-tangIBA 01/2017 - 12/2013
4	Pharmaceutical PreparationsIBA 01/2017 - 07/2005
4	Estrogens (Estrogen)FDA Link 04/2013 - 03/2005
4	Hormones (Hormone)IBA 06/2012 - 11/2003
4	Gonadotropin-Releasing Hormone (GnRH)FDA Link 06/2012 - 03/2005
4	Proteins (Proteins, Gene)FDA Link 04/2011 - 01/2008
3	Analgesics (Analgesic Drugs)IBA 01/2017 - 06/2016
3	Oxaliplatin (Eloxatin)FDA LinkGeneric 11/2016 - 01/2014
3	gosha-jinki-ganIBA 11/2016 - 01/2014
3	Indomethacin (Indometacin)FDA LinkGeneric 06/2016 - 03/2007
3	keishibukuryoganIBA 04/2016 - 03/2005
3	ChemokinesIBA 01/2013 - 06/2009
3	sairei-toIBA 01/2008 - 03/2006
3	ginger extractIBA 07/2005 - 03/2002
2	15- methyl- 8- aza- 16- oxagona- 1,3,5(10),13- tetraen- 17- one (MAOTO)IBA 01/2017 - 01/2017
2	shogaolIBA 01/2017 - 03/2002
2	shakuyaku-kanzoh-tohIBA 11/2015 - 01/2013
2	jumi-haidoku-toIBA 09/2015 - 01/2015
2	AndrogensIBA 01/2015 - 11/2004
2	Testosterone (Sustanon)FDA Link 01/2015 - 11/2004
2	Glutamic Acid (Glutamate)FDA Link 01/2014 - 01/2010
2	Interleukin-8 (Interleukin 8)IBA 01/2011 - 06/2008
2	Glycyrrhetinic Acid (Po 12)IBA 01/2010 - 04/2007
2	Glycyrrhizic Acid (Glycyrrhizin)IBA 01/2010 - 04/2007
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 05/2009 - 12/2006
2	Formaldehyde (Formol)FDA Link 05/2009 - 12/2006
2	GABA-A Receptors (GABA(A) Receptor)IBA 05/2009 - 12/2006
2	Estradiol (Delestrogen)FDA LinkGeneric 05/2008 - 11/2004
2	antiglomerular basement membrane antibodyIBA 01/2008 - 03/2006
2	Histamine (Histamine Dihydrochloride)FDA Link 06/2007 - 12/2002
2	calcitonin gene-related peptide (8-37)IBA 06/2007 - 03/2002
2	Progesterone FDA LinkGeneric 07/2005 - 11/2004
2	Calcitonin Gene-Related Peptide Receptor AntagonistsIBA 11/2003 - 03/2002
1	SaponinsIBA 01/2017
1	GhrelinIBA 01/2017
1	Ephedrine FDA LinkGeneric 01/2017
1	gingerolIBA 01/2017
1	Toll-Like Receptor 3IBA 01/2017
1	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 11/2016
1	bushiIBA 11/2016
1	methanesulfonate salt 2-hydroxy-4,4'-diamidinostilbeneIBA 06/2016
1	Acetic Acid (Vinegar)FDA LinkGeneric 06/2016
1	PowdersIBA 04/2016
1	BenserazideIBA 01/2016
1	Levodopa (L Dopa)FDA LinkGeneric 01/2016
1	boiogitoIBA 12/2015
1	AntioxidantsIBA 09/2015

Therapy/Procedure

14	Kampo Medicine (Kampo) 01/2018 - 12/2002
5	Therapeutics 01/2017 - 11/2004
5	Oral Administration 04/2016 - 07/2005
2	Radiotherapy 07/2015 - 01/2015
1	Analgesia 01/2017
1	Chemoradiotherapy 06/2016